Certified Nephrology Nurse Exam Practice 2025 – Complete Study Guide

Angiotensin II plays a critical role in renal physiology primarily by stimulating the release of aldosterone and causing vasoconstriction. When blood pressure drops or there is a decrease in blood volume, the renin-angiotensin-aldosterone system (RAAS) is activated, leading to the production of angiotensin II from angiotensin I. One of the key functions of angiotensin II is to constrict blood vessels, which helps to increase systemic vascular resistance and therefore blood pressure.

In addition to vasoconstriction, angiotensin II promotes the secretion of aldosterone from the adrenal glands. Aldosterone acts on the kidneys to enhance sodium (and consequently water) reabsorption, which helps restore blood volume and blood pressure. These mechanisms are essential for maintaining homeostasis and ensuring adequate perfusion of tissues, especially in the kidneys where proper function is vital for filtering blood and regulating electrolyte balance.

The other choices do not accurately reflect the primary functions of angiotensin II. While angiotensin II does influence renal blood flow indirectly, its predominant effects are on blood vessel constriction and the regulation of aldosterone, making option B the most accurate representation of its primary role in renal physiology.